Synthesis of magnetoliposomes with monodisperse iron oxide nanocrystal cores for hyperthermia

نویسندگان

  • Marcela Gonzales
  • Kannan M. Krishnan
چکیده

Heating rates generated by superparamagnetic particles deteriorate quickly with particle polydispersity. We prepared highly uniform, monodisperse, single-crystal magnetite nanoparticles of tailorable size via organometallic decomposition. As-synthesized nanocrystals were coated with phospholipids to form biocompatible magnetoliposomes. Modeling of AC-magnetic field parameters indicates that 11 nm nanocrystals have maximum heating rates within the biologically safe frequency range. r 2005 Elsevier B.V. All rights reserved.

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تاریخ انتشار 2005